Objectives: This study is aiming to measure the following biochemical parameters in the serum samples of autistic children that are recruited for this study:
1- Reduced glutathione (GSH) level.
2- Oxidized glutathione (GSSG) level.
Methods: A cross-sectional study that involves screening recently diagnosed autistic children in Oman, for GSH/GSSG ratio estimation using commercial assay kit, catalog #k264-100, Biovision Inc, USA.
Results: A low GSH/GSSG ratio indicates a cellular oxidative stress as evident by low level of reduced GSH as compared to oxidized GSH level.
Conclusions: Results of this study will emphasize the oxidative stress role in the pathogenesis of autism in Oman.