International Meeting for Autism Research: Biopsychosocial Model of ADHD in Autism Spectrum Disorder

Biopsychosocial Model of ADHD in Autism Spectrum Disorder

Friday, May 21, 2010
Franklin Hall B Level 4 (Philadelphia Marriott Downtown)
1:00 PM
K. Gadow , Psychiatry, State University of New York, Stony Brook, NY
Background: Clinic- and population-based studies indicate that ADHD symptoms are common in ASD. However, it is not clear whether these ADHD symptoms are similar to what is observed in children with ASD.

Objectives: Describes the initial results of programmatic research into a biopsychosocial model of nosology and pathogenesis for ADHD in children with ASD that integrates biomarkers and mental health risk factors with functioning in home and school setting.  

Methods: Children with ASD with and without ADHD, their parents, and teachers completed an extensive battery of measures about ADHD and co-occurring behavioral symptoms and psychosocial mental health risk factors and provided DNA samples (parents, child).  

Results: Findings indicate that children with and without ADHD exhibit marked differences in co-occurring symptomatology and mental health risk factors as well as differences between ADHD subtypes. ADHD symptoms are associated with social and academic functioning. ADHD also appears to be a distinct behavioral syndrome from other disruptive behavior disorders. Several candidate genes appear to be potential biomarkers for ADHD.

Conclusions: Findings provide initial support for and ADHD syndrome in children with autism that evidences both similarities and differences with ADHD in nonASD samples.

See more of: Comorbidities
See more of: Clinical & Genetic Studies