Objectives: To compare the homocysteine levels as a biomarker of autism in normal and autistic Omani children
Materials and Methods: This case control study evaluated eighty Omani children, 40 diagnosed autistic children (3-5 years of age) and 40 their age and gender matched controls. Fasting serum HCY levels were measured using an enzyme immunoassay (EIA) technique.
Results: The results indicated that the mean serum HCY levels were significantly higher in autistic children (20.1 ± 3.3 µmol/L) as compared to controls (9.64 ± 2.1 µmol/L ) as well as to the normal reference values (5-15 µmol/L) .
Conclusions: Our study suggests that high fasting serum level of HCY might be used as a biomarker for an early diagnosis and management of autism.
See more of: Animal Models & Cell Biology
See more of: Biological Mechanisms