Objectives: This study was aimed to compare the circulatory levels of leptin and adiponectin in normal and Omani autistic children.
Methods: The blood/plasma samples were collected from SQU hospital, Oman from autistic and control children. THe study was approved by SQU ethical committee. Quantitation leptin and adiponectin were done by using the kits from R & D systems, USA
Results: Reduced adiponectin and elevated leptin were found in Omani autistic children as compared with controls.
Conclusions: This is the first study in Omani autistic children about leptin and adiponectin. The outcome of this study may give a lead to develop novel biomarkers for early detection of autism. Also this study will give the relationship between adiponectin / leptin and the pathophysiology of autism.
See more of: Animal Models & Cell Biology
See more of: Biological Mechanisms