Objectives: This study was aimed to compare the status of circulatory enzymatic antioxidant status in normal and Omani autistic children.
Methods: We have analyzed the activities of plasma antioxidant enzymes such as superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px) by using commercially available kits.
Results: There was a significant reduction in the activities of the SOD, catalase and GSH-Px were observed in Omani autistic children as compared with controls, which shown an agreement with previous studies from other countries.
Conclusions: This is the first study in Omani autistic children about enzymatic antioxidant status and the outcome of this study may give a lead to develop a novel biomarker for early detection of autism. Also this study will give the relationship between oxidative stress and the pathophysiology of autism.
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