The Rdoc and Autism Research

Thursday, May 15, 2014: 2:20 PM
Marquis BC (Marriott Marquis Atlanta)
A. Wagner, NIH/NIMH, Bethesda, MD

The NIMH- initiated the Research Domain Criteria (RDoC) is an attempt to develop a framework to study mechanisms of mental disorders that cut across traditional boundaries of mental disorders, with the goal of facilitating research that aligns with genetics, other areas of neuroscience and behavioral science.   Many investigators have questions about the implications of the RDoC initiative for NIMH priorities, and whether there is an inherent conflict between RDoC classification and other psychiatric diagnostic entities such as the DSM-5.

Objectives:  To demonstrate the potential application of RDoC-relevant research in ASD, recent research findings from the autism field that fit the “spirit” of RDoC will be presented. 

Methods:  The method for the development of RDoC incorporates input from the scientific community, and is envisioned as an ongoing, iterative process.  This presentation will review the RDoC goals, the process of its development, and its role in ASD research.  There will be opportunities for discussion and questions from participants.   

Results:  The ultimate goal of RDoC  is to provide a foundation that can lead to more effective diagnosis, the identification of more homogeneous targets for interventions, and the development of new treatments or more precise matching of treatments to patients. 


Workshop participants will have a better understanding of NIMH goals with the development of RDoC and how this approach aligns with autism research.