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Thursday, May 7, 2009
Northwest Hall (Chicago Hilton)
1:30 PM
Background: The reported rates of Bipolar disorders(BP) in individuals with diagnosis of autism spectrum disorders (ASD) have shown great discrepancies, varying between 2.8% to 27% .The difference between the results of these studies seems related with methodological difficulties.
Objectives: The present study aimed to assess the rate of bipolar disorders in high functioning children and adolescents with diagnosis of Autism spectrum disorders.
Methods: Participants were from a private psychiatry center located in central city in Istanbul and autism clinic of child psychiatry department ,Istanbul School of Medicine. Ninety –Five individuals , 65 with diagnosis of Asperger’s disorder(AS) and 30 with diagnosis of autistic disorder(AD) ,age ranged between 6-20 years old(mean age:11.07+/_3.5) were included. Diagnosis of Asperger’s Disorder and Autistic disorder were made based on DSM-IV criteria. Only subjects with full IQ over 70 in WISC-R were included in the study. Co-morbidity of BP was assessed using the Schedule for Affective Disorders and Schizophrenia for School Age Children - Present and Lifetime Version (K-SADS - PL). Final diagnosis of BP was made based on Leibenluft’s “ the narrow phenotype” definition. Therefore, only subjects who meet the full criteria in DSM-IV-TR for hypomania or mania, including the duration criterion and also hallmark symptoms of elevated mood or grandiosity were diagnosed with BPD.
Results: 4 out of the 95 subjects received the diagnosis of Bipolar Disorders(4.2%).All were male.3 out of the 65 subjects with AS (4.4%)and 1 out of the 30 subjects with AD (3.3%)got the additional diagnosis of BP.
Conclusions: It could be concluded that BP is not a rare co-morbid condition in youth with diagnosis of ASD . Differential diagnosis of BPD disorder in subjects with ASD seems crucial in establishing an effective treatment program, and therefore improving mental health outcomes.
Objectives: The present study aimed to assess the rate of bipolar disorders in high functioning children and adolescents with diagnosis of Autism spectrum disorders.
Methods: Participants were from a private psychiatry center located in central city in Istanbul and autism clinic of child psychiatry department ,Istanbul School of Medicine. Ninety –Five individuals , 65 with diagnosis of Asperger’s disorder(AS) and 30 with diagnosis of autistic disorder(AD) ,age ranged between 6-20 years old(mean age:11.07+/_3.5) were included. Diagnosis of Asperger’s Disorder and Autistic disorder were made based on DSM-IV criteria. Only subjects with full IQ over 70 in WISC-R were included in the study. Co-morbidity of BP was assessed using the Schedule for Affective Disorders and Schizophrenia for School Age Children - Present and Lifetime Version (K-SADS - PL). Final diagnosis of BP was made based on Leibenluft’s “ the narrow phenotype” definition. Therefore, only subjects who meet the full criteria in DSM-IV-TR for hypomania or mania, including the duration criterion and also hallmark symptoms of elevated mood or grandiosity were diagnosed with BPD.
Results: 4 out of the 95 subjects received the diagnosis of Bipolar Disorders(4.2%).All were male.3 out of the 65 subjects with AS (4.4%)and 1 out of the 30 subjects with AD (3.3%)got the additional diagnosis of BP.
Conclusions: It could be concluded that BP is not a rare co-morbid condition in youth with diagnosis of ASD . Differential diagnosis of BPD disorder in subjects with ASD seems crucial in establishing an effective treatment program, and therefore improving mental health outcomes.