The treatment of day-time behavior for people with autism has challenged clinicians for many years. Most researchers and clinicians have solely concentrated on the treatment of what happens during the day – overlooking the possible influence of sleep on these behaviors. This panel provides evidence to support the relationship of day-time problems and symptoms to disrupted sleep for people with autism. Specifically, the panel will review the relationships of sleep disruption with a) cognitive and adaptive behavior, b) mental health (e.g., anxiety and depression), and c) behavior excesses (e.g., aggression). The panel will also address the research-based efficacy for a parent training protocol for treating sleep problems in children with autism.