Objectives: The purpose of this study is to examine the inter-rater reliability and the criterion-based validity of the Japanese version of the DISCO (DISCO-J). This is the first report on the DISCO-J.
Methods: The authorized Japanese translation of the eleventh version of the DISCO was used in interviews with parents of 22 children. 11 children had the diagnosis of Autism spectrum disorder (ASD) ( 89±22mths, M:F 8:3, mean IQ±SD 91.5±28.8) and 11 children were a sample with typical development （Age 75±23mths, M:F 3:8, IQ 102.8±14.1）. One DISCO-licensed child psychiatrist carried out the interviews, rated all items of DISCO-J and made clinical diagnoses based on the classifications of pervasive developmental disorders in the Diagnostic and Statistical Manual 4th edition Text Revision (DSM-IV-TR). Another DISCO-licensed child psychiatrist observed the interviews, rated all items of DISCO-J and then made independent diagnoses based on the DSM-IV-TR. The inter-rater reliability of the assessments by the two psychiatrists using the DISCO-J and the criterion-based validity of the diagnoses using the DISCO-J and the DSM-IV-TR were examined.
Results: There was a significant difference between the results for sex ratio（χ2=4.5, p=0.03）but no difference was observed for age and IQ between the ASD group and Non-ASD group. For the inter-rater reliability, Cohen’s kappa or intraclass correlation coefficient r was over 0.78 for all three sections of infancy, age of recognition / development and untypical behavior. For the diagnosis part,κor r was 0.88. For criterion based validity the concordance rate of DSM-DISCO diagnosis was 95% and κ was 0.91.
Conclusions: Based on this study, the DISCO-J appears to have good inter-rater reliability and criterion-based validity. Since these preliminary findings were for a small number of 22 subjects, it will be necessary to widen the study over a larger number of patients.
See more of: Clinical Phenotype
See more of: Symptoms, Diagnosis & Phenotype