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Cell Biological Mechanisms

This session presents abstracts on cellular mechanisms that may contribute to the autism phenotype including those defined in induced human progenitor cell lines, brain tissue, peripheral blood and genetic neuronal models.
Friday, 3 May 2013: 10:30-12:30
Chamber Hall (Kursaal Centre)
10:30
120.001
Generation and Neuronal Differentiation of Self-Renewing Neuronal Progenitor Cell Lines As a Model to Investigate Synaptic Development and Functions in Patients Affected by the Phelan-Mcdermid Syndrome (PMS)
D. I. Orellana E. Faggiani E. Fusar Poli L. Carlessi G. Bechi C. Vicidomini C. Sala C. Verpelli
10:45
120.002
Redox-Sensitive Protein Dynamics in Lymphoblastoid Cell Lines From Patients with Autism Spectrum Disorders
A. Chiocchetti D. Haslinger T. Karl S. Wiemann C. M. Freitag F. Poustka B. Scheibe J. Bauer H. Hintner M. Breitenbach J. Kellermann F. Lottspeich S. M. Klauck H. Breitenbach-Koller
11:00
120.003
Increased Susceptibility of Autism Lymphoblastoid Cells to Mitochondrial Dysfunction Following Reactive Oxygen Species Challenge
S. Rose R. E. Frye S. Melnyk R. A. Wynne S. J. James
11:15
120.004
Reduced Activities of Mitochondrial Electron Transfer Chain Complexes and Pyruvate Dehydrogenase in the Frontal Cerebral Cortex in Autism
A. Chauhan F. Gu V. Chauhan
11:30
120.005
Oxidative Stress Markers in Children with Autism Spectrum Disorders
M. E. Gonzalez Fraguela
11:45
120.006
JAKMIP1 Is a Novel Component of an FMRP-Associated RNP Complex and Regulates Neuronal Translation
J. M. Berg L. Chen A. Oguro-Ando J. L. Stein J. A. Miller A. A. Vashisht E. P. Kite A. Li O. Penagarikano J. A. Wohlschlegel D. H. Geschwind
12:00
120.007
Mutation of the PTCHD1 Gene, Which Encodes a Transmembrane Protein Expressed in Postsynaptic Dendritic Spines, Associated with Autism
M. A. Papon S. Marouillat C. Antar E. Cottereau P. Vourc'h S. Alirol C. Andres H. van Bokhoven J. Chelly H. Van Esch H. H. Ropers M. Raynaud A. Toutain F. Laumonnier
12:15
120.008
Maternal Innate Immune Activation by Poly(I:C) Induces the Expression of the Cytokines IL-1ƒ" and IL-13, Chemokine MCP-1, and Colony Stimulating Factor VEGF in Fetal Mouse Brain (Withdrawn)
 J. L. Bruses G. Arrode-Bruses
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