20365
Prediction of Intellectual Impairment By Developmental Assesments in Children with Autism Spectrum Disorder Compared to Globally Delayed Children
Objectives: To evaluate to trajectory of developmental delay in children with ASD and in children with GD without ASD.
Specific aim: to compare developmental assessment tools to subsequently performed cognitive test results in a population with ASD as compared to GD children.
Methods: Children (n=88) diagnosed with global developmental delay (delay of more than 2 SD in two or more areas of development), and assessed with Bayley 2 developmental test, were followed and reassessed after age four using cognitive tests (WIPPSI, Kaufman and WISC-R). They were divided in two groups according to definite diagnosis of ASD (n= 38, 26 males) or GD without ASD (n=50, 37 males).
Results: As expected, a positive correlation was found between lesser degree of developmental delay as measured by MDI and subsequent IQ, in both groups. From ASD group, 60.1% scored with significant delayed performance on developmental test and 66% from GD group without ASD were significantly delayed. Subsequently, on cognitive tests after age 4 years, 20% of the non-ASD GD group scored with an IQ less than 70 and 28.9% from ASD group scored with comorbid intellectual disability.
Conclusions: MDI score less that 65 on Bayley 2 performed before age 3 years, predicts lower IQ (less than 70), on subsequent cognitive assessments. However, developmental delay trajectory is more stable in ASD group than in globally delayed children.
See more of: Diagnostic, Behavioral & Intellectual Assessment